1. Treatment of Gastrointestinal Diseases

Antiflatulent Effect
Dimethicone can be used as an antiflatulent drug for the gastrointestinal tract. It can change the surface tension of gas bubbles, causing the foam in the gastrointestinal tract to burst, thereby relieving abdominal distension caused by gas accumulation. For symptoms of abdominal distension resulting from functional dyspepsia, irritable bowel syndrome, etc., the use of preparations containing dimethicone can effectively alleviate the discomfort. Common drugs such as Simethicone Emulsion are often used as adjuvants for gastroscopy and radiological examinations, helping to achieve clear imaging and improve the accuracy of the examination.

Protecting the Gastric Mucosa
In the acidic environment of the stomach, dimethicone can form a protective film covering the surface of the gastric mucosa, reducing the irritation and damage of gastric acid, pepsin, etc. to the gastric mucosa, and assisting in the treatment of gastric ulcers, gastritis, and other diseases.

2. Dermatological Applications

Skin Protectant
Taking advantage of the hydrophobicity and lubricity of dimethicone, it can form a protective film on the skin surface, isolating external irritants such as friction and chemical substances. For diaper dermatitis, intertrigo, etc., it can reduce skin friction, promote the repair of damaged skin, and relieve symptoms.

Assisting Drug Penetration
Due to its good solubility and low surface tension, dimethicone can be used as a drug carrier to help some poorly soluble drugs penetrate the skin better. For example, adding dimethicone to some topical antifungal and anti - inflammatory ointments can enhance the transdermal absorption of drugs and improve the therapeutic effect.

3. Applications in Otolaryngology and Ophthalmology

In the Ear
In the treatment of ear diseases, dimethicone can be used to soften cerumen (earwax), making it easier to excrete. At the same time, for the problem of thick secretions caused by some ear inflammations, it can reduce the surface tension of the secretions, facilitate drainage, and relieve the feeling of ear blockage.

In the Eye
As one of the components of artificial tears, dimethicone can increase the viscosity of the tear fluid, prolong the residence time of the tear fluid on the ocular surface, and relieve eye dryness symptoms. It is often used in the treatment of dry eye syndrome.

4. Surgical Aids

Anti - adhesion Material
In surgical operations, especially in abdominal and thoracic surgeries, postoperative tissue adhesion is a common complication. Dimethicone has good biocompatibility and lubricity. It can be applied or sprayed on the surgical wound surface to form an isolation film, reducing friction and adhesion between tissues, and reducing the incidence of postoperative adhesion.

5. Pharmaceutical Applications

Coating Material
In the coating process of solid preparations such as tablets and pills, dimethicone can be part of the coating material. It can improve the flexibility, water - resistance, and gloss of the coating, protect the drug from the external environment, control the drug release rate, and improve the stability of the drug and patient compliance.

Defoaming Agent
During the production of pharmaceutical preparations, such as in the fermentation process for preparing antibiotics and enzyme - based drugs, a large amount of foam is likely to be generated, affecting production. Due to its low surface tension, dimethicone can be used as an efficient defoaming agent to quickly eliminate foam and ensure the smooth progress of production.